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Archive for July, 2010

Severe burn injuries sustained whilst under inpatient psychiatric care—A worrying trend

Wednesday, July 28th, 2010

We have been concerned by a recent increasing trend that we have observed in the number of cases of self-inflicted burns in patients detained under section 3 of the UK Mental Health Act (2007). (Source: Burns : Journal of the International Society for Burn Injuries)

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Patient controlled sedation using a standard protocol for dressing changes in burns: Patients’ preference, procedural details and a preliminary safety evaluation. Are studies always adequately powered and analyzed?

Wednesday, July 28th, 2010

We are very pleased for the interest shown by Dr. Mangano and co-workers in our publication “Patient controlled sedation using a standard protocol for dressing changes in burns: Patients’ preference, procedural details and a preliminary safety evaluation” . We understand the scientific concern to have sufficiently powered studies in clinical as well as experimental studies. However, in the present context, in the early development phase of a clinical project like ours, such an aim, as suggested by Dr. Mangano et al. is both extensively costly, impractical and technically impossible to conduct. The reasons will be listed below. (Source: Burns : Journal of the International Society for Burn Injuries)
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Patient controlled sedation using a standard protocol for dressing changes in burns: Patients’ preference, procedural details and a preliminary safety evaluation. Are studies always adequately powered and analyzed?

Wednesday, July 28th, 2010

We read with interest the article published by Dr. Nilsson and colleagues . While the authors are to be commended for their aim to conduct a preliminary study to evaluate different sedation protocols during dress change in burned patients, there are several issues with both the design of the study and the statistical analysis used. (Source: Burns : Journal of the International Society for Burn Injuries)
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Survival area of super-thin flaps

Wednesday, July 28th, 2010

We would like to make some comments on a letter written by Dr. Prakash entitled “The pedicled super-thin flap for resurfacing defects due to burn” . Based on their past clinical experience with pedicled super-thin flaps, Dr. Prakash states in his letter that “Hyakusoku et al. failed to offer a rationale for the length and breadth of the flap that could be super-thinned”, and concluded that “it should be raised in a length:breadth ratio of 1:1 and the rest of the length of flap should not be thinned”. We believe that these comments show a lack of knowledge and understanding of our flaps. (Source: Burns : Journal of the International Society for Burn Injuries)
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Apparent high chloraemia in persons with deep third-degree burns: Interference linked to topical treatment

Wednesday, July 28th, 2010

In recent years, we observed cases of abnormally high chloraemia in some patients hospitalised at the Burn Treatment Center, which are not consistent with the remaining aspects of the patient’s hydro-electrolytic equilibrium. Disagreements are also observed between chloraemia measured by direct total arterial blood potentiometry (ABL™ 700, Radiometer™ blood gas analyser) and those measured by indirect potentiometry on plasmatic samples (Cobas Integra 800™, Roche Diagnostics). (Source: Burns : Journal of the International Society for Burn Injuries)
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Authors reply on the comment to “Platelet rich Plasma in burns” by Curinga et al

Wednesday, July 28th, 2010

Thank you for the comment on our article and the emphasis on the changes and effects of burn on the platelets itself. We agree with your statement that the increasing number of bedside kits available is somewhat irritating since they often do not explain the physiological impact. (Source: Burns : Journal of the International Society for Burn Injuries)

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Comments on “Platelet-rich plasma in burns”

Wednesday, July 28th, 2010

Authors’ should be congratulated for the review article “Platelet-rich plasma in burns” by Pallua et al. , which is exhaustive and clear. With the present communication, we would like to add a few considerations based on ours and other most recent experience. (Source: Burns : Journal of the International Society for Burn Injuries)
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The role of an ingestible telemetric thermometer in preventing exertional heat stroke, for a patient with healed massive burns running the 2007 London marathon

Wednesday, July 28th, 2010

Adequate thermoregulation relies upon an intact dermis and epidermis . Cutaneous vessels dilate to dissipate heat (“dry heat loss” via conduction, convection and radiation) and constrict in order to retain heat. Dermal sweat glands are vital adnexal structures required for heat loss during exercise via evaporation (“wet heat loss”). It is generally believed that extensive thermal damage to the integumentary system impairs thermoregulation for a variety of reasons. (Source: Burns : Journal of the International Society for Burn Injuries)
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